Today’s PrizePicks best picks and props of the day include game four of the Eastern Conference Finals between the Cleveland Cavaliers and the New York Knicks. Also featured are games from a full slate of MLB action.

Karl-Anthony Towns UNDER 17.5 Points

Prizepicks
May 21, 2026; New York, New York, USA; New York Knicks center Karl-Anthony Towns (32) reacts against the Cleveland Cavaliers during the second quarter of game two of the eastern conference finals of the 2026 NBA playoffs at Madison Square Garden. Mandatory Credit: Vincent Carchietta-Imagn Images

Karl-Anthony Towns has struggled to go over this line all throughout the NBA playoffs. He’s averaging 16.8 and has only scored 18 or more in two of his last nine games. His scoring ceiling is not high either, only going over the line by a few points when he does clear.

Landry Shamet OVER 8.5 PRA

PrizePicks
May 19, 2026; New York, New York, USA; New York Knicks guard Landry Shamet (44) reacts after making a three point basket against the Cleveland Cavaliers during overtime in game one of the eastern conference finals during the 2026 NBA playoffs at Madison Square Garden. Mandatory Credit: Brad Penner-Imagn Images

Landry Shamet has come up huge for the Knicks in the NBA playoffs. He’s had game where he’s been giving 25+ minutes due to his shooting ability. Since becoming a key rotation piece in New York, he’s gone over this PrizePicks line in 4/5 games.

Jacob Misiorowski OVER 7.5 Strikeouts

PrizePicks
May 13, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers starting pitcher Jacob Misiorowski (32) throws a pitch in the first inning against the San Diego Padres at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images

Jacob Misiorowski has been one of the best pitchers in the entire MLB this season. He leads the NL with 88 strikeouts and will have a chance to extend that lead on Monday. He’s gone over this PrizePicks line in eight of his last ten games.

Ben Brown UNDER 4.5 Hits Allowed

PrizePicks
May 14, 2026; Atlanta, Georgia, USA; Chicago Cubs pitcher Ben Brown (32) throws against the Atlanta Braves in the third inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images

Ben Brown has been fantastic in both roles he’s been used in this year. He’s transitioned into the starting rotation following the injury to Matthew Boyd and has had two good starts. This start against the Pittsburgh Pirates should be no different; expect him to keep the basepaths clear.

End Of My PrizePicks Rant

Today’s PrizePicks POTD is Misiorowski. Pair him with Shamet for the best 3x on today’s PrizePicks board. Remember to always bet responsibly; nothing should ever be considered a guarantee or lock.


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