NFL player props are one of the most fun markets in sports gambling today. Betting on your favorite players provides another level of commitment for the season. These player props are a lock in 2025. Every player on this list is due for a big season, and there is money to be made in the process. 

5. Rome Odunze Over 875 Receiving Yards (-115)

Jul 23, 2025; Lake Forest, IL, USA; Chicago Bears wide receiver Rome Odunze (15) walks with the ball during training camp at Halas Hall. Mandatory Credit: Kamil Krzaczynski-Imagn Images
Jul 23, 2025; Lake Forest, IL, USA; Chicago Bears wide receiver Rome Odunze (15) walks with the ball during training camp at Halas Hall. Mandatory Credit: Kamil Krzaczynski-Imagn Images

Rome Odunze is due for a breakout year in Chicago. Ben Johnson is his head coach, and Keenan Allen isn’t there to steal his targets. Luther Burden and Colton Loveland could affect his numbers, but Odunze is Caleb Williams’ guy. Last season, Odunze caught 54 passes for 734 yards and three touchdowns. Those numbers will easily see an increase in his second season. 

4. Bucky Irving 1,000+ Rushing Yards (-130)

Jan 12, 2025; Tampa, Florida, USA; Tampa Bay Buccaneers running back Bucky Irving (7) runs during the fourth quarter of a NFC wild card playoff against the Washington Commanders at Raymond James Stadium. Mandatory Credit: Nathan Ray Seebeck-Imagn Images
Jan 12, 2025; Tampa, Florida, USA; Tampa Bay Buccaneers running back Bucky Irving (7) runs during the fourth quarter of a NFC wild card playoff against the Washington Commanders at Raymond James Stadium. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

Bucky Irving broke onto the scene last season, and he’s set to be the workhorse of the Buccaneers’ running back room this season. Last season, he rushed the ball 207 times for 1,122 yards and eight touchdowns. He won’t have any issues getting over 1,000 rushing yards again in his second season. Tampa Bay’s run game will be lethal with Irving at the helm. 

3. Dak Prescott 4,000+ Passing Yards (+100)

Jul 27, 2025; Oxnard, CA, USA; Dallas Cowboys quarterback Dak Prescott (4) at training camp at the River Ridge Fields. Mandatory Credit: Kirby Lee-Imagn Images
Jul 27, 2025; Oxnard, CA, USA; Dallas Cowboys quarterback Dak Prescott (4) at training camp at the River Ridge Fields. Mandatory Credit: Kirby Lee-Imagn Images

If Dak Prescott doesn’t reach 4,000 passing yards in 2025, it will be embarrassing. He only played eight games last season due to an injury, but the last time he was healthy, he lit it up. In 2023, Prescott threw for 4,516 yards and a league-leading 36 touchdown passes. This season, he has Ceedee Lamb, George Pickens, and Jake Ferguson to throw to. The run game will be weak. Dallas will rely on Prescott’s arm to lead them to the promised land. 

2. TreVeyon Henderson 5+ Rushing TD’s (-175)

Aug 16, 2025; Minneapolis, Minnesota, USA; New England Patriots running back TreVeyon Henderson (32) runs with the ball against the Minnesota Vikings in the first quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-Imagn Images
Aug 16, 2025; Minneapolis, Minnesota, USA; New England Patriots running back TreVeyon Henderson (32) runs with the ball against the Minnesota Vikings in the first quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-Imagn Images

TreVeyon Henderson has an opportunity to do great things in his rookie season in the NFL. He shouldn’t have a problem outsnapping Rhamondre Stevenson. Five touchdowns feel like an easy lock considering his performance in the preseason. The 2025 NFL Draft had a stacked running back class, and Henderson has a chance to be the best of the bunch. 

1. T.J. Watt 12+ Sacks (-165)

Jul 24, 2025; Latrobe, PA, USA; Pittsburgh Steelers defensive end T.J. Watt (90) pressures quarterback Aaron Rodgers (8) during training camp at Saint Vincent College. Mandatory Credit: Charles LeClaire-Imagn Images
Jul 24, 2025; Latrobe, PA, USA; Pittsburgh Steelers defensive end T.J. Watt (90) pressures quarterback Aaron Rodgers (8) during training camp at Saint Vincent College. Mandatory Credit: Charles LeClaire-Imagn Images

T.J. Watt has played eight seasons in the NFL, and he has gone over 12 sacks in every season except three. He didn’t hit it in his rookie season, and he missed the mark in 2022 when he played ten games due ot an injury. Now that the Steelers’ secondary is good, Watt should be supplied with plenty of time to get home on quarterbacks. 12 sacks are an easy number for Watt in 2025.

End Of My NFL Rant

Jul 26, 2023; Irvine, CA, USA; A Wilson official NFL Duke football game ball on the field at Los Angeles Rams training camp at UC Irvine. Mandatory Credit: Kirby Lee-Imagn Images
Jul 26, 2023; Irvine, CA, USA; A Wilson official NFL Duke football game ball on the field at Los Angeles Rams training camp at UC Irvine. Mandatory Credit: Kirby Lee-Imagn Images

When betting player props, take these five lines into account. Injuries can derail player prop bets, but these are locks for the 2025 NFL season. These players will have no problem clearing these player prop bets this year. They’re all in a great situation to win people money.