Just because Sunday night comes to an end doesn’t mean there’s no value left in Week Six of the NFL schedule. Monday Night Football provides a rare double-header to squeeze the last best bets of the week. The Atlanta Falcons will host the Buffalo Bills, while the Washington Commanders host the Chicago Bears. All odds provided by Bodog, with stats and rankings provided by Fox Sports.

Best Bets – Falcons Vs. Bills Total Over 50.0 (-105)

Before being upset 23-20 by the New England Patriots last week, the Bills were averaging 33.25 PPG. There’s no reason to sound the alarm, as the Patriots always give them trouble, including winning three of the last five, and the two they lost were competitive, one-possession games. Excluding the head-to-head games in this rivalry, Buffalo hasn’t scored fewer than 27 points since October 14, 2025.

Best Bets
Oct 5, 2025; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) practices before the game at Highmark Stadium. Mandatory Credit: Mark Konezny-Imagn Images

The Falcons may not come to mind when thinking about some of the best offenses, but they rank seventh heading into Week Six. Their run-heavy team will score points on the Bills’ 28th-ranked run defense, contributing to this being on the list of best bets. It’s not enough to keep them in contention for the win, but don’t be surprised if they put up points in every quarter.

Best Bets – Quarterback Jayden Daniels Over 7.5 Carries (-114)

In his three games, Commanders’ quarterback Jayden Daniels has rushed seven, eight, and eleven times. He gets the added benefit of playing the Bears, who have the second-worst run defense in the NFL. The Sporting News reports that wide receiver Terry McLaurin is likely to miss a third consecutive game due to a quad injury, and that Deebo Samuel is back to limited practice, leaving questions about whether he will start. Daniels will carry the team Monday night.

Best Bets – Quarterback Michael Penix Jr. Under 223.5 Passing Yards (-115)

The Falcons’ passing yards have varied drastically based on their opponents. When playing top-ten pass defenses like the Vikings and Panthers, they averaged 153.5 yards per game. On the other hand, they averaged 305.5 against the sub-par pass defenses of the Commanders and Tampa Bay Buccaneers. The Bills are the highest-ranked pass defense this season for Atlanta so far. Look for the offense to go run-heavy to take advantage of the Bills’ biggest weakness.

End Of My Best Bets Rant

Gamblings is risky, and fans should bet only what they can afford to lose, but there’s no denying the reasoning behind these valuable choices. Go make the best of the NFL week ending and the beginning of the work.

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