Monday Night Football closes Week Six with the San Francisco 49ers hosting the Washington Commanders on Monday, October 19. San Francisco enters the matchup looking to protect its unbeaten record, while Washington hopes to bounce back after a tie with the New York Giants.
The game features several important injury concerns on both sides, including key players listed as out or questionable. Here’s everything you need to know about the kickoff time, TV coverage, streaming options and injury report for Commanders vs. 49ers.
The Commanders and 49ers are scheduled to kick off at 8:15 p.m. ET on Monday, October 19, 2026, at Levi’s Stadium in Santa Clara, California.
| Game Details | Information |
|---|---|
| Matchup | Washington Commanders at San Francisco 49ers |
| Date | Monday, October 19, 2026 |
| Kickoff | 8:15 p.m. ET |
| Stadium | Levi’s Stadium |
| TV Channels | ESPN and ABC |
| Streaming | ESPN platforms and NFL+ options, subject to subscription and device restrictions |
Fans can watch the game on ESPN or ABC. Streaming availability depends on the service, subscription and device being used, so check your provider before kickoff.
For the full slate of games, see the NFL Week Six schedule.
The 49ers have significant injury concerns heading into Monday night. Deebo Samuel is listed as out with a hamstring injury, while defensive star Nick Bosa is also unavailable, according to the injury information in the current report.
Samuel’s absence would leave San Francisco without one of its versatile offensive playmakers. Bosa’s status is particularly important on defense, where his pass-rushing ability can put pressure on opposing quarterbacks.
Their absences could force other players to take on larger roles as the 49ers try to maintain their unbeaten start.
Mike Evans and Christian Kirk are listed as questionable for San Francisco, making their availability important to watch before kickoff. Evans has been dealing with rib and Achilles concerns, while Kirk has a calf issue.
If either player is limited or unavailable, the 49ers could need additional contributions from their other receivers. Their final status should be confirmed through the latest official injury report before the game.
Washington also has injury problems heading into the matchup. Running back Jacory Croskey-Merritt is listed as out with a groin injury, along with Marcus Mariota, Javontae Jean-Baptiste and Charles Omenihu. Stefon Diggs is listed as questionable with a hamstring injury.
These absences could affect Washington on both sides of the ball. The Commanders will need their available players to step up, particularly if Diggs cannot play.
For the latest updates, check the official NFL injury report before kickoff.
San Francisco enters the matchup at 5-0 and will look to continue its strong start. The 49ers are coming off a reported 32-29 win over Seattle, a game in which they forced four turnovers.
Washington, meanwhile, is coming off a 27-27 tie against the Giants. The Commanders will need a stronger performance to challenge San Francisco on the road.
Three factors could shape Monday night’s game:
San Francisco has the stronger record entering the matchup, but injuries could play a major role in how the game unfolds.
The Commanders and 49ers wrap up Week Six on Monday night, with kickoff scheduled for 8:15 p.m. ET on ESPN and ABC. San Francisco will try to extend its unbeaten run, while Washington looks to get back on track after its tie with New York.
Check the final injury report before kickoff for the latest player updates, and confirm streaming availability with your provider so you don’t miss the action.
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