We are officially past the halfway point of the season as we enter NFL Week 10. Teams are fighting over their respective divisions, while some are closing in on a playoff spot. Here is a full preview of NFL Week 10, with picks and score predictions for every game.
Washington Commanders (2-5-1) @ New York Giants (5-2-1)
The Giants are on a two-game win streak following their Week 6 loss to the New Orleans Saints. The week prior, they tied with the Commanders in overtime. New York’s offense looks vastly different this time as J.J. McCarthy enters his third game under center.
Washington is 1-2 since tying with the Giants, and without multiple key players from their previous meeting. Defensive tackle Daron Payne, center Lucas Patrick, wide receiver Terry McLaurin, running back Jacory Croskey-Merritt, and DT Javon Kinlaw are all out of action.
Both teams want to make up for the tie in Week 5, and both are missing plenty of key players. The Giants have momentum on their side and have looked like the better team over the last five weeks.
Score Prediction: Giants 20 – Commanders 17
New England Patriots (5-4) Vs. Detroit Lions (6-2)
The Patriots are coming off a disastrous performance in their 45-27 loss to the Green Bay Packers. Drake Maye went 21/38 for 299 yards, three touchdowns, and three interceptions. They’re down to Corey Kiner at running back following injuries to TreyVeyon Henderson and Rhamondre Stevenson.
The Lions were underwhelming in a 19-9 victory over the Miami Dolphins. Jared Goff went 17/25 for 170 yards and an interception, while Jahmyr Gibbs rushed 20 times for 74 yards and a touchdown. Neither team looks terrific, but Detroit is in a healthier spot.
Score Prediction: Lions 27 – Patriots 23
Kansas City Chiefs (6-2) @ Atlanta Falcons (3-6)
The Chiefs bounced back in a 35-12 victory over the New York Jets, largely thanks to a 21-point second-half surge. They recently acquired wide receiver Josh Downs to aid in the offense, and Kenneth Walker rushed for over 100 yards for the first time since Week 6.
The Falcons continued to struggle in a 34-17 loss to the Cincinnati Bengals in Madrid. Joe Burrow went 24/29 for 271 yards and three touchdowns against a defense that is now without Jessie Bates III. This is a tough matchup for Atlanta, especially given the state of the NFC South.
Score Prediction: Chiefs 27 – Falcons 20
Houston Texans (3-5) @ Cleveland Browns (5-4)
The Texans came back from their bye week with a much-needed 44-22 win over the Los Angeles Chargers. C.J. Stroud looks like the best version of himself, with 2,251 passing yards, 16 touchdowns, and two interceptions. The defense is still struggling to regain form, but looks better than it did at the start of the year.
The Browns have leveled out after a 5-2 start, losing both of their last two games. Deshaun Watson is expected back under center, but he hasn’t played on Stroud’s level this season. Houston has a chance to finally stack wins.
Score Prediction: Texans 24 – Browns 17
Minnesota Vikings (6-2) @ Green Bay Packers (6-3)
After an abysmal showing on Monday night, the Vikings traded for QB Kirk Cousins in hopes of reviving their offense. With the Las Vegas Raiders, Cousins has logged 2,340 yards, 20 touchdowns, and eight interceptions. He should adjust to his former team’s scheme fairly quickly.
The Packers are coming off an electric 45-27 win over the Patriots. Jordan Love went 23/29 for 372 yards and three touchdowns. Green Bay has found a spark despite a lackluster run game. Now, they’ll face a defense that logged four sacks and an interception in their Week 1 matchup.
Score Prediction: Packers 23 – Vikings 21
Miami Dolphins (1-7) @ Indianapolis Colts (2-7)
The Dolphins have struggled all season on both sides of the ball. They’ve put up a fight in each of their last two games. With Malik Willis on injured reserve, Kyle McCord will start at QB.
The Colts are nearly lifeless at this point of the season. They’re on a five-game losing streak, and traded away several key players over the last two weeks. They did, however, take the Dallas Cowboys down to the wire in Week 9. Neither team is overly exciting, but Indy is less of a question mark right now.
Score Prediction: Colts 17 – Dolphins 13
Carolina Panthers (3-5) @ New Orleans Saints (3-5)
The Saints escaped overtime with a 23-22 win over the Browns thanks to a defensive stop on a two-point conversion. Their run game found some life behind Audric Estime’s 72 yards and a touchdown. They have a tough division matchup in NFL Week 10.
The Panthers are on a three-game losing streak and fired DC Ejiro Evero two weeks ago. While they have plenty of talent on the roster, they haven’t been able to put it together. Though, that is the case with the entire NFC South.
Score Prediction: Panthers 27 – Saints 24
Buffalo Bills (7-1) @ New York Jets (2-7)
The Bills overcame the Vikings’ defense on Monday night in a 23-6 win and extended their record to 7-1. Josh Allen, while not perfect, is playing terrific football. Behind a strong run game and a defense that just acquired safety Amani Hooker, they’re a bona fide contender.
The Jets are on a different path than their division rival. They’re on a four-game losing streak, despite keeping some of those games close. This is a messy division matchup, so it may be close, but it shouldn’t be.
Score Prediction: Bills 31 – Jets 20
Jacksonville Jaguars (6-2) @ Tennessee Titans (1-7)
The Jaguars have been one of the NFL’s most impressive teams over the past 12 months. Their two losses this season came by a combined 10 points, and they’ve outscored their last two opponents 75-17. Now, after acquiring DT Jordan Davis and safety Jessie Bates, they’re all in on a Super Bowl run.
The Titans are the complete opposite of Jacksonville in 2026. With one win on the season and a top-three draft pick in sight, their season is already lost. The development of QB Cam Ward is their top priority, but it seems to be a long road.
Score Prediction: Jaguars 34 – Titans 17
Los Angeles Rams (5-4) @ Arizona Cardinals (3-6)
The Rams are now without Davante Adams and Puka Nacua going into a meeting with a division rival that already beat them this season. The duo of Myles Garrett and Aaron Donald finally saw the field in Week 9, and it led them to a much-needed win over the Commanders.
The Cardinals are on their third quarterback of the season in rookie Carson Beck. After trading Jacoby Brissett, Gardner Minshew suffered a torn UCL in his right arm, sidelining him for the season. With number one receiver Michael Wilson also on IR, the Rams are looking at a perfect revenge game.
Score Prediction: Rams 23 – Cardinals 13
Seattle Seahawks (5-4) @ Las Vegas Raiders (4-5)
The Fernando Mendoza era is officially here after the Raiders traded Kirk Cousins to Minnesota. The Raiders have played fairly well this season, but struggle against playoff contenders. The 2026 first-overall pick has waited for this moment, and he’s walking into a trial by fire.
The Seahawks’ QB situation has been messy with injuries to Sam Darnold and Drew Lock. The latter is still set to play, but the strength lies in the defense. Seattle ranks first in total yards allowed per game (244.2) and fourth in points allowed per game (18). A rookie QB facing off with the reigning Super Bowl champions can get ugly fast.
Score Prediction: Seahawks 19 – Raiders 13
San Francisco 49ers (7-1) @ Dallas Cowboys (4-5)
The Cowboys put the Colts away thanks to a late interception from rookie Caleb Downs. They still, however, allowed Indy to exceed 20 points for the first time since Week 5. Their defense ranks 30th in total yards allowed per game (372.7) and 25th in points allowed per game (26.2).
The 49ers are still arguably the best team in the NFL, even with a laundry list of injuries. The offense is seventh in the NFL in total yards per game (351.4) and first in touchdowns (31). Brock Purdy and Co. should have some fun here.
Score Prediction: 49ers 31 – Cowboys 23
Pittsburgh Steelers (6-2) @ Cincinnati Bengals (6-2)
The Steelers are coming off their bye week after a four-game win streak. Their offensive line has come together, and Aaron Rodgers’ retirement tour is looking great. They’ll be tested against a division rival that’s seemingly found its groove.
The Bengals’ defense, while not always dominant, is finally a threat to opposing teams. The unit holds up when it matters most, and the offense is humming behind Joe Burrow. This is the best Cincy has looked since its last playoff appearance nearly five years ago.
Score Prediction: Bengals 30 – Steelers 27
Los Angeles Chargers (0-8) @ Baltimore Ravens (4-5)
The Chargers looked completely hapless in their 44-22 loss to the Texans. Justin Herbert was sacked eight times and went 13/23 for 193 yards, a touchdown, and an interception. Nothing has gone right for them, and now Herbert is playing through a hand injury.
The Ravens are expected to start Jacoby Brissett after a dismal showing from rookie UDFA Joe Fagnano. Their defense has only 17 sacks this season, tied for 19th in the NFL. The Chargers can’t lose every game, but they have a perfect Week 11 matchup to fix that.
Score Prediction: Ravens 23 – Chargers 17
Bye Week: Chicago Bears, Denver Broncos, Philadelphia Eagles, Tampa Bay Buccaneers
End Of My NFL Week 10 Rant
The NFL trade deadline set the stage for some exciting games in Week 10. Cousins’ return to Minnesota, Mendoza’s first start, and a suped-up defense in Jacksonville are top stories to watch on Sunday. November football is in full swing, and the race to Super Bowl LXI is heating up.
